About Cingal
Cingal was developed by OrthogenRx, a company focused on creating innovative solutions for joint pain management. The product was designed to provide patients with a combination of lubrication (from HA) and pain relief (from the corticosteroid) in a single injection, offering a dual mechanism of action. Cingal was approved by the FDA as a treatment for knee osteoarthritis, providing a non-surgical option for patients struggling with joint pain.
How It Works?
Cingal is an injectable treatment for osteoarthritis (OA) that combines hyaluronic acid and triamcinolone acetonide. The hyaluronic acid provides lubrication and shock absorption, improving joint movement and reducing pain caused by friction. The triamcinolone (steroid) component reduces inflammation, alleviating swelling and discomfort. This dual-action approach offers rapid pain relief and longer-term symptom management, providing up to 6 months of relief and improving joint function, making it an effective non-surgical solution for knee OA.
Key Features
- Easy, one-shot therapy.
- Highly concentrated HA derived from non-animal sources.
- Within days of injection, steroids offer quick, transient pain relief.
- Both the first and subsequent injections have a strong safety profile.
- For up to six months, the HA Visco-supplement offers sustained pain relief.
- Cingal’s 2014 pivotal clinical research showed that it could give those with knee OA quick and sustained pain relief.
- Patients can restore joint function and lessen discomfort thanks to the combination of anti-inflammatory actions and lubrication, which offer quick pain relief and long-term symptom management.
Results
- Immediate: Immediate pain relief after the injection and reduced inflammation and swelling in the knee joint.
- After 1 to 2 Weeks: Improvement in joint stiffness and better comfort and mobility.
- After 4 to 6 Weeks: Significant, long-lasting pain relief and improved joint function.
Composition
- 88 mg Hyaluronic Acid
- 18 mg Triamcinolone Hexacetonide


